WELLNESS SCREEN DNA TEST
WHAT IS IT?
A multi-gene DNA test routinely added to an assessment of blood cholesterol and glucose levels, blood pressure and body mass index (BMI) as part of Wellness Programs offered by healthcare practitioners.
It includes analysis of variation in clinically useful genes that may contribute to abnormal cholesterol levels, homocysteine accumulation, blood clotting, iron overload, and inflammation. Some of these abnormalities contribute to the development of type II diabetes, obesity, and hypertension. Oxidative stress, detoxification or carcinogens, and oestrogen exposure are also important considerations in this context.
This pathology supported genetic test is performed in conjunction with an assessment of any food allergy or intolerances known to be associated with many chronic disorders. The results of the genetic test are combined with clinical indicators and lifestyle factors to identify a combination of risk factors that may lead to disease development or progression if left untreated.
WHEN DO WE RECOMMEND IT?
For individuals that show features of having metabolic syndrome, characterized by three or more of the following clinical conditions: central obesity, hypertension, glucose intolerance and dyslipidemia. Also for those people looking to be proactive about health and lifestyle.
This genetic service is an extension of standard health checks such as cholesterol and glucose testing. The aim is to determine the most likely cause of possible abnormal blood levels and at the same time identify genetic determinants of response to environmental exposures such as diet and use of medication that may also affect health outcomes in future. This information is summarised in a comprehensive report provided to guide risk reduction intervention from the genetic background.
Completion of the Medical History and Lifestyle Questionnaire when this test is requested or considered might furthermore highlight the presence of clinical conditions or metabolic indicators linked to the development of chronic disorders of lifestyle or a family history of a monogenic disease that may require further genetic counseling or testing. The Wellness GeneScreen may, therefore, be considered as a screening step for extended clinical work-up.
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